Metal-organic frameworks (MOFs) structural properties and electrochemical detection capability for cancer biomarkers

Metal-organic frameworks (MOFs) are a prominent porous material for cancer biomarkers detection. They are enriched with unique features of permanent porosity and tunable pore size, leading to their efficient use in biosensing. In this review, we have summarized and studied MOF materials for the electrochemical detection of cancer biomarkers. First, insight into the tunable porosity and surface areas have been discussed to explore the applicability of MOFs. MOFs porosity and functional sites are critical to the development of the sensor. Then, MOF biosensors for target cancer biomarkers detection have been discussed. In addition, the MOFs biosensors challenges and future direction are discussed to provide next-generation biosensors.