Fibrin IS present in plastic bronchitis casts and can impact treatment!

Pediatric PulmonologyEarly View COMMENTARY Fibrin IS present in plastic bronchitis casts and can impact treatment! Deborah R. Liptzin MD, MS, Corresponding Author Deborah R. Liptzin MD, MS [email protected] Department of Pediatrics, University of Washington, Seattle, Washington, USA Correspondence Deborah R. Liptzin, MD, MS, Department of Pediatrics, University of Washington, Seattle, WA, USA. Email: [email protected] Contribution: Conceptualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorLivia A. Veress MD, Livia A. Veress MD orcid.org/0000-0003-4981-9634 Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA Contribution: Writing - review & editing, SupervisionSearch for more papers by this author Deborah R. Liptzin MD, MS, Corresponding Author Deborah R. Liptzin MD, MS [email protected] Department of Pediatrics, University of Washington, Seattle, Washington, USA Correspondence Deborah R. Liptzin, MD, MS, Department of Pediatrics, University of Washington, Seattle, WA, USA. Email: [email protected] Contribution: Conceptualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorLivia A. Veress MD, Livia A. Veress MD orcid.org/0000-0003-4981-9634 Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA Contribution: Writing - review & editing, SupervisionSearch for more papers by this author First published: 17 April 2024 https://doi.org/10.1002/ppul.27017Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Briski K, Labib B, Hussain S, Ramagopal M, Uppaluri L. Novel therapies for eosinophilic pediatric plastic bronchitis. Pediatr Pulmonol. 2024. 10.1002/ppul.26974 PubMedWeb of Science®Google Scholar 2Liptzin DR, McGraw MD, Houin PR, Veress LA. Fibrin airway cast obstruction: experience, classification, and treatment guideline from Denver. Pediatr Pulmonol. 2022; 57(2): 529-537. 10.1002/ppul.25746 PubMedWeb of Science®Google Scholar 3Wolfe AG, Stillwell PC, Veress LA. Significant airway obstruction by carbonaceous fibrin casts in a child with smoke inhalation injury. Am J Respir Crit Care Med. 2024. 10.1164/rccm.202212-2289IM Web of Science®Google Scholar 4Bodmer JL, Weinman J, Veress LA, Galambos C. Obstructive bronchial fibrin cast formation in COVID-19 severe respiratory failure. Am J Respir Crit Care Med. 2023; 207(3): 349-350. 10.1164/rccm.202201-0225IM PubMedWeb of Science®Google Scholar 5Veress LA, Anderson DR, Hendry-Hofer TB, et al. Airway tissueplasminogen activator prevents acute mortality due to lethal sulfur mustardinhalation. Toxicol Sci. 2015; 143(1): 178-184. 10.1093/toxsci/kfu225 CASPubMedWeb of Science®Google Scholar 6Racz J, Mane G, Ford M, et al. Immunophenotyping and proteinprofiling of Fontan-associated plastic bronchitis airway casts. Ann Am ThoracSoc. 2013; 10(2): 98-107. 10.1513/AnnalsATS.201209-080OC CASPubMedGoogle Scholar 7Heath L, Ling S, Racz J, et al. Prospective, longitudinal study of plasticbronchitis cast pathology and responsiveness to tissue plasminogen activator. Pediatr Cardiol. 2011; 32(8): 1182-1189. 10.1007/s00246-011-0058-x PubMedWeb of Science®Google Scholar 8Do TB, Chu JM, Berdjis F, et al. Fontan patient with plastic bronchitis treated successfully usingaerosolized tissue plasminogen activator: a case report and review of theliterature. Pediatr Cardiol. 2009; 30(3): 352-355. 10.1007/s00246-008-9312-2 PubMedWeb of Science®Google Scholar 9Gibb E, Blount R, Lewis N, et al. Management of plastic bronchitis with topicaltissue-type plasminogen activator. Pediatrics. 2012; 130(2): e446-e450. 10.1542/peds.2011-2883 PubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation