医学
血管成形术
心脏病学
放射科
接收机工作特性
颈动脉支架置入术
内科学
单光子发射计算机断层摄影术
数字减影血管造影
颈动脉
金标准(测试)
颈内动脉
狭窄
减法
核医学
血管造影
颈动脉内膜切除术
算术
数学
作者
Keita Yamauchi,Yukiko Enomoto,Katharina Otani,Yasuyuki Egashira,Toru Iwama
标识
DOI:10.1136/neurintsurg-2017-013259
摘要
Background Hyperperfusion syndrome after carotid interventions has a low incidence but it can lead to morbidity and mortality. Objective To evaluate the usefulness of quantitative DSA for predicting hyperperfusion phenomenon (HPP) after carotid artery stenting and angioplasty. Methods Thirty-three consecutive patients with carotid stenosis treated with carotid artery stenting or angioplasty between February 2014 and August 2016 were included. Color-coded digital subtraction angiograms showing the time to maximum contrast intensity of each image pixel were obtained from conventional DSA before and after procedures. The cerebral circulation time (CCT) was defined as the difference in the relative time to maximum intensity between arterial and venous regions of interest set on the angiograms. HPP was diagnosed straight after the procedure with qualitative 123 I-IMP single-photon emission CT (SPECT). Cut-off points for detecting HPP for preprocedural CCT and periprocedural change of CCT were assessed by receiver operating characteristic analysis using 123 I-IMP SPECT as reference standard. Results 123 I-IMP SPECT showed HPP in 4 of 33 patients. In these 4 patients, preprocedural prolongation of CCT (13.0±6.1 vs 7.2±1.3 s; p<0.001) was seen compared with patients without HPP as well as larger periprocedural changes of CCT (5.9±5.7 vs 0.5±1.3 s; p<0.001). The optimal cut-off points of preprocedural CCT and change of CCT for predicting HPP were 8.0 s (100% sensitivity, 69% specificity) and 3.2 s (75% sensitivity, 100% specificity), respectively. Conclusions Preprocedural prolongation and greater periprocedural change of CCT are associated with the occurrence of HPP. Periprocedural evaluation of CCT may be useful for predicting HPP.
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