Antifungal antibiotic against fruit rot disease of red pepper from Streptomyces parvullus.

A strain producing active compound against Phytophthora capsici and Phytophthora parasitica was selected from 4,087 strains of Actinomycetes isolated from domestic soil. This strain was identified as Streptomyces parvullus by the cultural, morphological and physiological characteristics. The active compound was purified from culture broth by ion-exchange, adsorption, gel permeation and partition column chromatography and identified as polyoxin by the physicochemical and biological properties. This is the first report that polyoxin is active against fruit rot disease of red pepper and is positive antagonizer of detoxin to Phytophthora capsici and Pyricularia oryzae.