癌变
基底细胞
长非编码RNA
头颈部鳞状细胞癌
癌症研究
癌症
生物
头颈部
生物信息学
细胞
医学
计算生物学
头颈部癌
核糖核酸
内科学
基因
遗传学
外科
作者
Lei Feng,Wei Chen,Wu Qiu
出处
期刊:PubMed
日期:2019-10-01
卷期号:23 (20): 8888-8896
被引量:2
标识
DOI:10.26355/eurrev_201910_19284
摘要
Oral squamous cell carcinoma (OSCC) is one of the most common and fatal diseases in the head and neck region worldwide. To better understand the carcinogenesis and to find efficient biomarkers and therapeutic targets are still in urgent need. The studies of expression profile and mechanisms of long non-coding RNAs (lncRNAs) develop fast in recent years. This molecule form is aberrantly expressing and influencing many cellular processes in different cancer types. But its expression pattern and association with oral squamous cell carcinoma are yet to be elucidated. Here we reviewed recently reported OSCC-related lncRNAs and their relationship with the clinical status of patients. Functional mechanisms were also discussed. With the emerging knowledge and techniques in this area, more efficient biomarkers and therapeutic targets are promising in the future.
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