医学
蛛网膜下腔出血
结果(博弈论)
格拉斯哥结局量表
改良兰金量表
血管痉挛
动脉瘤
麻醉
作者
Alexander Hammer,Gholamreza Ranaie,Eduard Yakubov,Frank Erbguth,Markus Holtmannspoetter,Hans-Herbert Steiner,Hendrik Janssen
出处
期刊:Aging
[Impact Journals, LLC]
日期:2020-04-20
卷期号:12 (8): 7207-7217
被引量:3
标识
DOI:10.18632/aging.103069
摘要
In this observational study, we analyzed and described the dynamics of the outcome after aneurysmal subarachnoid hemorrhage (SAH) in a collective of 203 cases. We detected a significant improvement of the mean aggregate modified Rankin Score (mRS) in every time interval from discharge to 6 months and up to 1 year. Every forth to fifth patient with potential of recovery (mRS 1-5) at discharge improved by 1 mRS point in the time interval from 6 month to 1 year (22.6%). Patients with mRS 3 at discharge had a remarkable late recovery rate (73.3%, p = 0.000085). Multivariate analysis revealed age ≤ 65 years (odds ratio 4.93; p = 0.0045) and World Federation of Neurological Surgeons (WFNS) grades I and II (odds ratio 4.77; p = 0.0077) as significant predictors of early improvement (discharge to 6 months). Absence of a shunting procedure (odds ratio 8.32; p = 0.0049) was a significant predictor of late improvement (6 months to 1 year), but not age ≤ 65 years (p = 0.54) and WFNS grades I and II (p = 0.92). Thus, late recovery (6 month to 1 year) is significant and independent from age and WFNS grade.
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