Synthesis and cyclization of benzo[ c ][1,2]dithiol-3-ones

Although benzo[c][1,2]dithiol-3-ones are a class of potentially biologically active drugs, there have been few reports on their new synthesis strategies and applications in organic synthesis in recent years. This article provides an overview of the synthesis methods of benzo[c][1,2]dithiol-3-ones and their involvement in cyclization reactions in recent years. We categorized the cycloaddition reactions involving benzo[c][1,2]dithiol-3-ones into five headings, such as [4 + 1] cycloadditions, [4 + 1 + 1] cycloadditions, [4 + 2] cycloadditions, [4 + 3] cycloadditions, and [4 + 4] cycloadditions. The fact showed that these cycloaddition strategies were very effective and provided various heterocyclic compounds with ideal results. In addition, the mechanisms of some cycloaddition reactions have also been discussed in this article.