环境化学
污染物
脂质过氧化
化学
谷胱甘肽
神经毒性
抗氧化剂
生物转化
锌
生物化学
毒性
酶
有机化学
作者
Alessia Cuccaro,Matteo Oliva,Lucia De Marchi,Matilde Vieira Sanches,Gianluca Bontà Pittaluga,Valentina Meucci,Federica Battaglia,Dario Puppi,Rosa Freitas,Carlo Pretti
标识
DOI:10.1016/j.marpolbul.2022.113601
摘要
With the increase of UV filters usage and consequent release into aquatic environments, the concerns about their potential ecological risks are also increasing. According to this, in the present study, adult polychaetes of the species Ficopomatus enigmaticus were chronically exposed to three concentrations (0.01, 0.1 and 0.5 mg/L) of organic and inorganic filters (Ethylhexyl methoxycinnamate (EHMC) and nanoparticulate Zinc oxide (nZnO), respectively) in order to analyse biochemical responses related to cellular damage, antioxidant defence, biotransformation mechanisms and, lastly, neurotoxicity. Despite major lipid peroxidation caused by EHMC was observed, both UV filters have produced the same response patterns. In details, a clear concentration-dependent activation of glutathione S-transferases and a significant decrease of acetylcholinesterase levels defined an important neurotoxic effect was observed for both contaminants. These results become important to expand the limited scientific literature on biochemical responses of marine and brackish water invertebrates to organic and inorganic UV filters.
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