细胞外基质
分解代谢
纤维化
医学
细胞生物学
糖酵解
化学
细胞外
生物化学
内科学
新陈代谢
生物
作者
Joshua D. Rabinowitz,Gökhan M. Mutlu
标识
DOI:10.1038/s42255-018-0013-8
摘要
Fibrosis is characterized by excessive extracellular matrix (ECM) production relative to catabolism. A new study shows that the fuel choice of fibroblasts impacts this balance, with glycolysis promoting ECM synthesis and fatty acid oxidation stimulating ECM degradation.
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