ChemInform Abstract: Diastereoselective Synthesis of Novel 5‐Substituted Morpholine‐3‐phosphonic Acids: Further Exploitation of N‐Acyliminium Intermediates.

Abstract Diastereoselective nucleophilic addition of trimethyl phosphite to an N‐acyliminium intermediate derived from substrate (I) gives cyclic α‐aminophosphonates.