载体(分子生物学)
病毒载体
基因传递
向性
遗传增强
临床试验
组织向性
风险分析(工程)
计算机科学
医学
计算生物学
生物技术
病毒学
生物
生物信息学
病毒
基因
遗传学
重组DNA
作者
Ekramy E. Sayedahmed,Rashmi Kumari,Suresh K. Mittal
出处
期刊:Methods in molecular biology
日期:2019-01-01
卷期号:: 155-175
被引量:18
标识
DOI:10.1007/978-1-4939-9065-8_9
摘要
Various adenovirus (AdV) vector systems have proven to be lucrative options for gene delivery. They can serve as potential vaccine candidates for prevention of several common infectious diseases and hold the promise for gene therapy, especially for cancer. Several AdV vector-based therapies are currently at various stages of clinical trials worldwide, which make an immense interest of both the clinicians and researchers. Since these vectors are easy to manipulate, have broad tropism, and have the capability to yield high titers, this delivery system has a wide range of applications for different clinical settings. This chapter emphasizes on some of the current usages of AdV vectors and their production methods.
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