Poly(lactic acid) (poly lactide,PLA)isa biocompatible and bioresorbable polymer,thus it is widely used in the medical area,and is paid much attention to.There are two main methods to synthesis PLA,ring- open- ing polymerization of lactide and condensation polymerization of lactic acid.In the paper,the process of the new re- search of the synthesis PLA was reviewed.Beside,the PLA synthesis methods of reactive extrusion and direct melting polycondensation were introduced,which are two high efficiency methods.Finally,the foreground of PLA synthesis was prospected.