ANALYSIS ON EPIDEMIOLOGICAL CHARACTERISTICS OF CASES OF MEASLES VACCINE IMMUNITY FAILURE IN GUANGDONG PROVINCE DURING 2004-2008

[Objective]To analyse the epidemiological characteristics of cases of measles vaccine immunity failure and the relevant factors in Guangdong Province during 2004-2008.[Methods]Descriptive epidemiological study was applied to analyse the data from reporting system of infectious diseases and measles monitoring system during 2004-2008.[Results]A total of 8 197 cases of measles vaccine immunity failure were reported in Guangdong Province during 2004-2008.The cases were reported in every city in Guangdong Province.More cases of measles vaccine immunity failure were reported in Shenzhen,Guangzhou,Zhongshan and Dongguan city.However,the proportion of measles cases was different in different regions.There were more cases from April to July each year.There weren't differences in the month of distribution and the total cases(Z =-0.17,P = 0.87).The sex ratio for men and women of measles vaccine immunity failure cases was 1:0.75(4 694/3 503).The rate of the floating measles vaccine immunity failure cases in the total immunity failure cases was 55.80%(4 574/8 197).The age distribution in measles vaccine immunity failure cases and the total cases was the significantly different(Z =-2.88,P = 0.00).The age distribution in measles vaccine immunity failure cases in different regions and years were the significantly different(region:χ2 = 707.78,P = 0.00,year:χ2 = 35.21,P = 0.00).[Conclusion]Measles vaccine immunity failure cases are found with a certain percentage in measles cases.It is worth of paying attention to the fact that the floating population and the younger-age cases.