Objective To explore the efficacy of assisted reproduction methods for infertile patients with polycystic ovary syndrome. Methods 98 infertility patients that suffering from polycystic ovary syndrome in Huadu District MCH from January 2012 to January 2014,their clinical data were retrospectively analyzed, the patients were given appropriate treatment for different causes of infertility,such as lifestyle adjustments,ovulation induction therapy,surgery and assisted reproductive therapy. Results There were 91 infertility patients with polycystic ovary syndrome successful pregnancy after the treatment,the effective rate was 92.86%. Conclusion it have get better clinical efficacy of lifestyle adjustments,ovulation induction therapy, surgery and assisted reproductive therapy for infertile patients with polycystic ovary syndrome,it conducive to patients with normal pregnancy.