Research Advances on the Relationship between Cell Senescence and Oxidative Stress,p16,p53/p21

The mechanisms of cell senescence mainly contain exterior oxidative stress theory and interior senescence-associated genes regulation theory.In recent years,the research on cell senescence pathway induced by reactive oxygen species and the regulation of senescence-associated genes,like p16,p53/p21 gains significant progress,clarifying the mechanisms of cell senescence further.With the extension of the knowledge on cell senescence,the projects on the profound benefits of cell senescence and on the relationship between cell senescence and individual aging,tumorigenesis have also drawn more and more attention.