Ultrafast Preparation of Monodisperse Fe3O4 Nanoparticles by Microwave‐Assisted Thermal Decomposition

Abstract Thermal decomposition, as the main synthetic procedure for the synthesis of magnetic nanoparticles (NPs), is facing several problems, such as high reaction temperatures and time consumption. An improved a microwave‐assisted thermal decomposition procedure has been developed by which monodisperse Fe 3 O 4 NPs could be rapidly produced at a low aging temperature with high yield (90.1 %). The as‐synthesized NPs show excellent inductive heating and MRI properties in vitro. In contrast, Fe 3 O 4 NPs synthesized by classical thermal decomposition were obtained in very low yield (20.3 %) with an overall poor quality. It was found for the first time that, besides precursors and solvents, magnetic NPs themselves could be heated by microwave irradiation during the synthetic process. These findings were demonstrated by a series of microwave‐heating experiments, Raman spectroscopy and vector‐network analysis, indicating that the initially formed magnetic Fe 3 O 4 particles were able to transform microwave energy into heat directly and, thus, contribute to the nanoparticle growth.