Comparison of the clinical efficacy of percutaneous vertebroplasty and percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture

Objective To investigate and compare the curative effect of percutaneous vertebroplasty( PVP)and percutaneous kyphoplasty( PKP) in the treatment of osteoporotic vertebral compression fracture( OVCF). Methods A total of 68 patients diagnosed with OVCF and hospitalized from Apr. 2011 to Feb. 2013 in our hospital were randomly divided into PVP group and PKP group. Visual analogue scale( VAS),vertebral compression rate and other indicators were observed and compared between the two groups. Results The operation time and bone cement injection amount were( 39. 72 ± 6. 82) min/vertebra and( 6. 11 ± 1. 73) m L/vertebra in PKP group,respectively,which were significantly higher than those of PVP group( P 0. 05); The VAS scores were significantly improved compared with preoperative ones in both PVP group and PKP group,but the VAS scores at each time point had no significant difference between the two groups( P 0. 05); The vertebral compression rate of the two groups was significantly improved compared with preoperative,but the vertebral compression rate of the PKP group was lower than that of PVP group at each time point( P 0. 05); The cement leakage rate of PKP group( 25. 53%) was significantly lower than that of the PVP group( 46. 51%) and the difference was statistically significant( P 0. 05). The average hospital cost of PVP group was( 10. 26 ± 1. 1) thousand yuan and significantly lower than that of PKP group[( 4. 97 ± 0. 23) thousand yuan,P 0. 05]. Conclusion Both PVP and PKP can effectively relieve pain of the OVCF patients. PKP is more conducive to the restoration of vertebral height and leads to less bone cement leakage but demands higher hospital cost.