Survival analysis of comprehensive radiotherapy and chemotherapy treatment for locally advanced nasopharyngeal carcinoma

Objective To analyze affect of the inducing chemotherapy plus the concurrent comprehensive application of radiotherapy and chemotherapy on survival rate of nasopharyngeal carcinoma. Methods One hundred and forty-three patients with stage Ⅲ nasopharyngeal carcinoma and 94 patients with ⅣA nasopharyngeal carcinoma treated in our hospital from January 1998 to December 1999 were selected and divided into the comprehensive radiotherapy and chemotherapy group with 164 patients and the simple radical radiotherapy group with 73 patients. The short-term survival rate, namely the complete remission rate, local tumor control rate and survival rate, of the two groups were compared. Results In comprehensive radiotherapy and chemotherapy group the complete remission rate, local tumor control rate and survival rate were significantly higher than the simple radical radiotherapy group (P 0.05). Conclusion The inducing chemotherapy plus the concurrent comprehensive application of radiotherapy and chemotherapy can improve the remission rate, local tumor control rate and survival rate for patients with locally advanced nasopharyngeal carcinoma, is a reasonable and effective treatment method for the locally advanced nasopharyngeal carcinoma, and can be widely applied in clinical treatment.