Secondary Metabolites by Chemical Screening. 30. Helmidiol, a New Macrodiolide from Alternaria alternata

Chemical screening of Fungi imperfecti strains resulted in the detection, isolation, and structure elucidation of a new symmetric 16-membered macrodiolide, named helmidiol ( 1 ). This secondary metabolite from Alternaria alternata (strain FH-A 6965) shows anthelmintic properties.