杂色曲霉素
抗真菌
化学
立体化学
麦角甾醇
分子
苯甲酸
绝对构型
有机化学
生物化学
生物
微生物学
真菌毒素
食品科学
作者
Hideyuki Seya,Koohei Nozawa,Shōichi Nakajima,Ken‐ichi Kawai,Shun‐ichi Udagawa
出处
期刊:Journal of the Chemical Society
日期:1986-01-01
卷期号:: 109-109
被引量:50
摘要
Together with ergosterol, sterigmatocystin, and emericellin, a new compound designated emestrin (1), C27H22H2O10S2, was isolated from the mycelial extract of Emericella striata. Violaceic acid (6) was also isolated from the culture filtrate. The structure of emestrin (1), including the absolute configuration, was determined on the basis of a spectroscopic investigation of some derivatives and X-ray crystallography of emestrin methanol solvate. Emestrin is a new macrocyclic epidithiodioxopiperazine, derived from two molecules of phenylalanine and one molecule of benzoic acid, and has strong antifungal activity.
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