洗脱
化学
人体净化
放射化学
辐照
分离过程
萃取(化学)
中子俘获
中子辐照
杂质
锕系元素
色谱法
核化学
分析化学(期刊)
硼
核物理学
物理
有机化学
作者
E. Philip Horwitz,Daniel R. McAlister,Alan M. Bond,Richard E. Barrans,James M. Williamson
标识
DOI:10.1016/j.apradiso.2005.02.005
摘要
A conceptual flowsheet has been developed for the separation of 177Lu from a 300 mg neutron irradiated 176Yb enriched target. The key component of the process is an extraction chromatographic (EXC) resin containing 2-ethylhexyl 2-ethylhexylphosphonic acid (HEH[EHP]) sorbed onto a 25–53 μm Amberchrom CG-71 substrate. The process is divided into three sections: (1) front-end target removal system, (2) primary separation system and (3) secondary separation system. Each section involves the separation of Yb and Lu using the HEH[EHP] resin followed by concentration and acid adjustment of the Lu-rich eluate using an EXC material containing a diglycolamide extractant. The use of the diglycolamide EXC material is a significant feature of the flowsheet, allowing one to avoid lengthy evaporations and acidity adjustments between successive HEH[EHP] column runs while removing adventitious impurities from the 177Lu. The overall recovery of 177Lu is estimated at 73% with an overall decontamination factor from Yb of 106. The overall processing time can be as short as 4 h.
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