褐藻糖胶
纳米颗粒
复合数
化学
化学工程
钙
壳聚糖
多糖
材料科学
有机化学
复合材料
工程类
作者
Hong Zhang,Haozhan Feng,Junhong Ling,Xiao–kun Ouyang,Xiaoyong Song
标识
DOI:10.1016/j.ijbiomac.2021.11.039
摘要
In this study, zein and fucoidan-based composite nanoparticles were prepared by the antisolvent precipitation method. The effects of different calcium ion (Ca2+, 0-3.0 mM) concentrations on the stability of the composite nanosystems loaded with quercetin were studied under different conditions (pH, temperature, salt concentration, and ultraviolet light irradiation), and the composite nanoparticles were characterized. Electrostatic interactions, hydrogen bonding, and hydrophobic interactions are the main forces underlying the formation of composite nanoparticles. The addition of Ca2+ led to improved release of the active substances from the composite nanoparticles in simulated digestive solutions (especially when the Ca2+ concentration was 1.5 mM). The composite nanosystems based on alcohol-soluble proteins and anionic polysaccharides with added Ca2+ can be potentially applied for the delivery of active substances.
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