Doubt about antidepressant-like effect

Dear Editor: Extensive studies have measured antidepressant-like effects of chemical compounds to discover new drugs for depression treatment or to clarify the molecular mechanisms of depression. Most useful antidepressants including tricyclics, selective serotonin reuptake inhibitors (SSRIs), noradrenaline reuptake inhibitors (NRIs), serotonin and noradrenaline