医学
代谢控制分析
1型糖尿病
观察研究
体质指数
内科学
糖尿病
2型糖尿病
血红蛋白
统计显著性
儿科
内分泌学
作者
Ángela Figueroa Sobrero,Patrícia Gonçalves Evangelista,Carmen Mazza,Pablo Basso,Stella M López,Edith Scaiola,Margarita Honf,Mabel Ferraro,M Eandi,Florencia Walz
出处
期刊:PubMed
[National Institutes of Health]
日期:2010-04-01
卷期号:108 (2): 130-5
被引量:6
标识
DOI:10.1590/s0325-00752010000200007
摘要
Eating disorders associated to type 1 diabetes (T1D) raise the risk of impairments in metabolic control increasing short and long term complications.To compare the glycosylated hemoglobin (HbA1c) levels variation in a group of T1D adolescents with and without disordered eating behaviour (DEB) during 3-year follow-up and to relate the metabolic control, with pubertal stage, T1D duration, Body Mass Index and gender at the end of the study.Analytyc an observational comparative study of two cohorts: patients were selected from a previous multicentric study done by the Paediatric Committee of the Argentinean Diabetes Association. One DEB sample group and another group without DEB were conformed. HbA1c levels were estimated al baseline and after 3 years. Pubertal stage, BMI, gender and duration of T1D were assessed at the end of the study. Comparison of statistical tests of HbA1c levels and association tests were made.Eighty seven patients, 22 with DEB and 65 without DEB were studied. Patient's mean ages (13.6 vs.14.3 years) and T1D evolution time (4.0 vs. 4.7 years) were similar in both groups. Three years later, there was an increase in the mean HbA1c levels in both groups, with statistical differences only in the DEB group (8.40 vs. 9.93) (p: 0.001), but not in the group without DEB [8.57 vs. 9.01 (p: 0.06)]. An association between metabolic control and the presence of DEB was observed but not with the other studied variables.Presence and persistence DEB in T1D patients implies a worsening prognosis of the metabolic control in the future.
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