免疫系统
干细胞
干扰素
细胞
生物
程序性细胞死亡
免疫学
癌症研究
细胞生物学
细胞凋亡
遗传学
作者
Shuichiro Takashima,M. Laura Martín,Suze A. Jansen,Ya–Yuan Fu,J. Bos,Daniel J. Chandra,Margaret O'Connor,Anna Mertelsmann,Paola Vinci,Jason Kuttiyara,Sean M. Devlin,Sabine Middendorp,Marco Calafiore,Anastasiya Egorova,M. Kleppe,Yuan-Hung Lo,Noah F. Shroyer,E. Cheng,Ross L. Levine,Chen Liu
出处
期刊：Science immunology
[American Association for the Advancement of Science]
日期：2019-12-06
卷期号：4 (42)
被引量：120
标识
DOI：10.1126/sciimmunol.aay8556
摘要
T cell–derived interferon-γ can directly target intestinal stem cells to induce their apoptosis in a JAK/STAT-dependent manner (see the related Focus by Kretzschmar and Clevers ).
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