败血症
代谢组
蛋白质组
代谢组学
感染性休克
医学
严重败血症
重症监护医学
生物信息学
内科学
生物
作者
Raymond J. Langley,Ephraim L. Tsalik,Jennifer C. van Velkinburgh,Seth W. Glickman,Brandon Rice,Chunping Wang,Bo Chen,Lawrence Carin,Arturo Suarez,Robert P. Mohney,Debra H. Freeman,Mu Wang,Jinsam You,Jacob Wulff,J. Will Thompson,M. Arthur Moseley,Stephanie J. Reisinger,Brian T. Edmonds,Brian W. Grinnell,David R. Nelson
标识
DOI:10.1126/scitranslmed.3005893
摘要
A molecular signature, derived from integrated analysis of clinical data, the metabolome, and the proteome in prospective human studies, improved the prediction of death in patients with sepsis, potentially identifying a subset of patients who merit intensive treatment.
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