Palladium‐Catalyzed Silver‐Mediated α‐Arylation of Acetic Acid: A New Approach for the α‐Arylation of Carbonyl Compounds

Abstract A new approach for the α‐arylation of acetic acid through Pd‐catalyzed silver‐mediated direct CH arylation of acetic acid with aryl iodides was developed. This protocol provided a straightforward method for the synthesis of a diverse set of α‐phenylacetic acids.