蛋白激酶C
蛋白激酶B
泡沫电池
MAPK/ERK通路
CD36
罗特勒林
细胞生物学
PI3K/AKT/mTOR通路
小干扰RNA
小发夹RNA
分子生物学
激酶
化学
信号转导
基因敲除
生物
细胞培养
转染
生物化学
受体
巨噬细胞
细胞凋亡
体外
遗传学
作者
Chin‐Sheng Lin,Feng‐Yen Lin,Ling‐Jun Ho,Chien‐Sung Tsai,Shu-Mung Cheng,Wan-Lin Wu,Chuan-Yueh Huang,Chen-Hao Lian,Shih-Ping Yang,Jenn-Haung Lai
摘要
AimsThe formation of foam cells is crucial in the initiation and progression of atherosclerosis. One of the critical steps in foam cell formation is the uptake of low-density lipoprotein (LDL) by macrophages via scavenger receptors (SRs). This study examined the role of protein kinase C (PKC) isoforms on foam cell formation.
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