Leveraging Human Mobility Data for Efficient Parameter Estimation in Epidemic Models of COVID-19

Effectively predicting the evolution of COVID-19 is of great significance to contain the pandemic. Extensive previous studies proposed a great number of SIR variants, which are efficient to capture the transmission characteristics of COVID-19. However, the parameter estimation methods in previous studies are based on data from epidemiological investigations, which inevitably have caused a large delay. The popularity of digital trajectory data world-wide makes it possible to understand epidemic spreading from human mobility perspective. The major advantage of digital trajectory data lies in that the co-location level of a population is reflected at every moment, making it possible to forecast the evolution in advance. We showed that the mobility data contributed by mobile phone users could be exploited to estimate the contact probability between individuals, thus revealing the dynamic transmission of COVID-19. Specifically, we developed an estimation method to obtain human co-location levels and quantified the variations of human mobility during the epidemic. Then, we extended the infection rate with a real-time co-location level to further forecast the transmission of an epidemic, predicting the epidemic size much more accurately than conventional methods. Finally, the proposed method was applied to evaluate the quantitative effect of different non-pharmacological interventions by predicting the epidemic situations with various mobility characteristics. The empirical results and simulations corroborated our theoretical analysis, providing effective guidance to contain the pandemic.