Research Trends and Hot Topics of Nanozymes in Wound Care: A Bibliometric Analysis

Nanozymes, as innovative enzyme mimics, hold significant promise for wound care, including antibacterial properties and tissue regeneration. Given their potential to transform wound management, this study utilizes advanced bibliometric tools to provide a comprehensive analysis of the nanozyme research landscape. The analysis covers various aspects, including publication trends, institutional contributions, journal coverage, and author involvement, offering a holistic view of research dynamics. It reveals the evolution of nanozyme research across different phases of wound healing by examining keyword co-occurrence frequencies and timeline developments. In addition, the study identifies emerging research clusters within these phases, focusing on three key areas: enhancing nanozyme performance, integrating them with hydrogel matrices, and developing responsiveness to external stimuli. These clusters highlight the increasing sophistication and diversity of nanozyme-based solutions for wound care. Furthermore, the study explores the intersection of nanozyme research with artificial intelligence (AI) and wearable sensors. This integration presents unprecedented opportunities for real-time monitoring, personalized treatment plans, and predictive analytics in wound care. The findings indicate a growing interest in this interdisciplinary field, pinpointing research frontiers centered around AI-driven wound assessment, continuous monitoring through wearable technologies, and the application of AI algorithms in nanozyme-based wound dressings. In summary, this bibliometric study provides a comprehensive global overview of research trends, key literature, hotspots, and emerging frontiers in nanozyme-based wound care. By investigating the synergy between AI, wearable sensors, and nanozymes, it elucidates the potential for novel and personalized treatment strategies in this rapidly advancing field.