Photocatalytic Decarboxylation of Carboxylic Acids by Iron Catalysis for the Construction of C(sp3)O Bonds under Visible Light

The facile construction of C(sp 3 )O bonds holds significant importance in organic synthesis. Herein, a visible‐light‐driven iron‐catalyzed decarboxylation of alkyl carboxylic acids is reported, enabling C(sp 3 )O bond formation through the trapping of generated alkyl radicals with TEMPO. This method is characterized by its low cost, broad substrate compatibility, and operational simplicity. Not only does it provides an efficient approach to C(sp 3 )O bond construction, but also it demonstrates potential applications in synthetic chemistry through subsequent modifications of TEMPO derivatives.