Photocatalytic Decarboxylative Hydroalkylation of Alkynes and Alkenes

A photocatalyzed radical decarboxylative hydroalkylation of alkynes and alkenes has been developed for the efficient synthesis of allylamine and arylpropylamine derivatives. This protocol employs organic 4CzIPN as a photocatalyst and avoids the use of transition metals, featuring simple and mild conditions. The mechanistic study suggested that the reaction was preceded by the decarboxylation of amino acids to give alkyl radicals, followed by radical addition to a carbon–carbon triple bond or double bond. A range of arylpropylamines were prepared with up to 88% yields, and allylamines were synthesized with good Z -selectivities. This process represents an important approach for the high-value-added transformation of unsaturated hydrocarbons under simple and mild conditions.