Effect of Orostachys iwarenge Hara on the proliferation of dermal papilla ceIls

In this study, we investigated the hair-growth effect ofplants growing in Jeju by the proliferation of dermal papilla cells. Dermal papilla cells are specialized mesenchymal cells that located at the bulb region of hair follicles. The cells play crucial roles in hair formation, growth, and cycling. When immortalized vibrissa dermal papilla cells were treated with several extracts, the extract of Orostachys iwarenge Hara increased proliferation of immortalized vibrissa dermal papilla cells. These results suggest that O. iwarenge extract has the potential to promote hair growth via the proliferation of dermal papilla.