滤泡性淋巴瘤
淋巴瘤
MAPK/ERK通路
癌症研究
生物
节的
BCL10
医学
肿瘤科
内科学
遗传学
免疫学
信号转导
作者
Abner Louissaint,Kristian T. Schafernak,Julia T. Geyer,Alexandra E. Kovach,Mahmoud Ghandi,Dita Gratzinger,Christine Roth,Christian N. Paxton,Sunhee S. Kim,Chungdak Namgyal,Ryan D. Morin,Elizabeth A. Morgan,Donna Neuberg,Sarah T. South,Marian H. Harris,Robert P. Hasserjian,Ephraim P. Hochberg,Levi A. Garraway,Nancy L. Harris,David M. Weinstock
出处
期刊:Blood
[American Society of Hematology]
日期:2016-08-25
卷期号:128 (8): 1093-1100
被引量:109
标识
DOI:10.1182/blood-2015-12-682591
摘要
Key Points PTNFL is a biologically distinct indolent lymphoma characterized by common MEK/ERK pathway mutations. The biology of PTNFL is not defined by age, as the mutational profile is similar in pediatric and adult cases.
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