Expression of PTEN and MTA1 and their Correlation in the Endometrial Cancer

Objective: To explore the expression of PTEN and MTA1 and their correlation in the endometrial cancer.Methods: In 130 cases of endometrial cancer and 40 cases of normal endometrial,the expression of PTEN and MTA1 was examined with immunohis-tochemistry SP method and their correlation.Results: The expression of PTEN and MTA1 in endometrial cancer was higher than that in normal endometrial.(P0.01).PTEN expression levels in endometrial cancer were inversely correlated with MTA1 protein.(r=-0.35,P0.05).Conclusion: Expression of PTEN expression and MTA1 is inversely correlated with the development and progression of en-dometrial cancer.