医学
克拉斯
胰腺癌
内科学
突变
癌症
胰腺
癌症研究
结直肠癌
遗传学
生物
基因
作者
John H. Strickler,Hironaga Satake,Thomas J. George,Rona Yaeger,Antoine Hollebecque,Ignacio Garrido‐Laguna,Martin Schüler,Timothy F. Burns,Andrew L. Coveler,Gerald S. Falchook,Mark Vincent,Yu Sunakawa,Laëtitia Dahan,David L. Bajor,Sun Young Rha,Charlotte Lemech,Dejan Juric,Marko Rehn,Gataree Ngarmchamnanrith,Pegah Jafarinasabian
标识
DOI：10.1056/nejmoa2208470
摘要
Sotorasib showed anticancer activity and had an acceptable safety profile in patients with KRAS p.G12C-mutated advanced pancreatic cancer who had received previous treatment. (Funded by Amgen and others; CodeBreaK 100 ClinicalTrials.gov number, NCT03600883.).
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