Stereochemical Editing

Abstract Stereochemical editing has recently risen to prominence, allowing the direct editing of organic molecules with stereocenter(s) to adjust their relative stereochemistry at a late‐stage. Several seminal light‐driven stereochemical editing reactions such as deracemization and epimerization have been successively developed. Recently, Wendlandt and co‐workers reported a versatile photochemical epimerization of unactivated tertiary stereogenic centers to rapidly prepare the stereoisomers that were previously challenging to access.