医学
置信区间
糖尿病
2型糖尿病
探血
牙科
队列
牙周炎
内科学
内分泌学
作者
Misuzu Sato,Sachiko Ono,Hayato Yamana,Akira Okada,Miho Ishimaru,Yosuke Ono,Masanori Iwasaki,Jun Aida,Hideo Yasunaga
摘要
Abstract Aim This study aimed to elucidate the impact of periodontal therapy on glycaemic control in individuals with type 2 diabetes and various baseline blood glucose levels using a large‐scale claims database from Japan. Materials and Methods Using the JMDC Claims Database, we identified individuals with type 2 diabetes who underwent health check‐ups in the fiscal years 2018 or 2019 and were followed up until the next year's health check‐up. We conducted a weighted cohort analysis using stabilized inverse probability weights for treatment and censoring to estimate the effect of periodontal therapy on changes in haemoglobin A1c levels within a year. Analysis was done for different baseline haemoglobin A1c categories: 6.5%–6.9%, 7.0%–7.9% and ≥8.0%. Results Of the 4279 insured persons included in the study, 957 received periodontal therapy. Overall, there was a tendency towards improved glycaemic control among those who received periodontal therapy. Participants with baseline haemoglobin A1c levels of 7.0%–7.9% who received periodontal therapy exhibited significantly better glycaemic control compared with those without dental visits (difference; −0.094 [95% confidence interval: −0.181 to −0.007]). Conclusions Periodontal therapy may improve glycaemic control in individuals with diabetes, especially in those with haemoglobin A1c levels ≥7.0%.
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