Antioxidant Activity of Metal-Organic Frameworks

Metal–organic frameworks (MOFs) have emerged as a captivating class of porous materials with diverse applications in various scientific domains. This chapter focuses on understanding the antioxidant activity of MOFs, a novel aspect that has received much interest in recent years. Antioxidants are critical in reducing oxidative stress and its adverse effects on biological systems. MOFs, with their complicated structure and customizable characteristics, provide a novel platform for developing antioxidant materials. The chapter starts with an overview of oxidative stress and its effects on human health and the environment. It then delves into the unique structural characteristics of MOFs that contribute to their potential as effective antioxidants. The design strategies for tailoring the antioxidant properties of MOFs are discussed, encompassing the incorporation of transition metals, organic ligands, and functional groups. Moreover, the methodologies employed for evaluating the antioxidant activity of MOFs are critically examined, encompassing both in vitro and in vivo approaches.