Palladium-catalyzed [6 + 4] cycloaddition with π-allyl all-carbon 1,6-dipole for the synthesis of ten-membered heterocycles

This work introduces a novel α,α-diester-δ-vinylvalerolactone as a dipolar precursor in a palladium-catalyzed [6 + 4] cycloaddition reaction with azadienes, resulting in the production of ten-membered heterocycles.