奎宁酸
化学
葡萄糖苷
咖啡酸
色谱法
立体化学
生物化学
医学
病理
替代医学
抗氧化剂
作者
Jiabo Cheng,Lequn Qiu,Naveed Ahmad,Jie Liu,Miao Tian,Chunying Li,Chunjian Zhao
标识
DOI:10.1080/14786419.2023.2171416
摘要
ES contains compounds known to have significant anti-fatigue activity. In recent years, it has received extensive attention because it is efficient. However, its active ingredients on antifatigue effect are still unclear. This study attempts to establish the spectrum-effect relationship of ES antifatigue activity to screen the effective components. The results showed that the similarity of 15 ES fingerprints obtained by LC-MS/MS was 0.533-0.992, and the chemical structures of 22 common peaks were identified. The anti-fatigue activity of 15 batches of ES was characterized by forced swimming test of mice and quantified by CAFI, among which S4, S1 and S5 had better activity. 9 components (caffeic acid, 5-(4-O-β-D-glucosylferoyl)-quinic acid, (±)13-HODE, isofraxidin, eleutheroside E, syringin, pinoresinol diglucoside or its isomer, 7,8-dihydrodehydrocarbinol alcohol-4-O-β-D-glucoside, secoisolariciresinol-4-O-β-D-glucoside) highly related to anti-fatigue activity may be the effective components of ES.
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