曲妥珠单抗
医学
癌症
伊立替康
内科学
危险系数
化疗
肿瘤科
胃肠病学
紫杉醇
外科
置信区间
乳腺癌
结直肠癌
作者
Kohei Shitara,Yung‐Jue Bang,Satoru Iwasa,Naotoshi Sugimoto,Min‐Hee Ryu,Daisuke Sakai,Hyun Cheol Chung,Hisato Kawakami,Hiroshi Yabusaki,Jeeyun Lee,Kaku Saito,Yoshinori Kawaguchi,Takahiro Kamio,Akihito Kojima,Masahiro Sugihara,Kensei Yamaguchi
标识
DOI:10.1056/nejmoa2004413
摘要
Therapy with trastuzumab deruxtecan led to significant improvements in response and overall survival, as compared with standard therapies, among patients with HER2-positive gastric cancer. Myelosuppression and interstitial lung disease were the notable toxic effects. (Funded by Daiichi Sankyo; DESTINY-Gastric01 ClinicalTrials.gov number, NCT03329690.).
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