Chinese guidelines for diagnosis and treatment of malignant lymphoma 2018 (English version)

Lymphoma is one of the most common malignancies in China.According to the report from the Chinese National Cancer Center, the incidence of lymphoma in China is 5.94/100,000 in 2014, and the estimated incidence of 2015 is 6.89/100,000.Due to the complexity of pathological classification in lymphoma and related distinctions in treatment, in order to improve standardization of diagnosis and therapy in lymphoma and to cooperate the safeguards for the supply of anti-tumor medicine, here we are updating and revising Chinese guidelines for diagnosis and treatment of malignant lymphoma (2015 edition). Diagnosis of lymphomaThe diagnosis of lymphoma should integrate clinical manifestation with physical, laboratory, imaging and pathological examinations. Clinical manifestationsThe manifestation of lymphoma includes systemic and local symptoms.Systemic symptoms include fever of unknown origin, night sweating, weight loss, skin itching and fatigue.Local symptoms depend on the primary and invaded sites of lesions.Lymphoma may originate from any organ or tissue of the body, and it is usually divided into two categories -from lymph node and extra lymph node.The most common manifestation is painless progressive lymphadenectasis.Patients with the above symptoms should be paid attention to, and be referred to superior hospitals or tumor hospitals as soon as possible. Physical examinationSpecial attention should be paid to the enlargement of lymph nodes in different regions, the size of liver and Guidelines