医学
肝病
酒
内科学
免疫学
胃肠病学
生物
生物化学
作者
Maria Effenberger,Anissa A. Widjaja,Felix Grabherr,Benedikt Schaefer,Christoph Grander,Lisa Mayr,Julian Schwaerzler,Barbara Enrich,Patrizia Moser,Julia Fink,Alisa Pedrini,Nikolai Jaschke,Alexander Kirchmair,Alexandra Pfister,Bela Hausmann,Reto Bale,Daniel Putzer,Heinz Zoller,Sebastian Schäfer,Petra Pjevac
出处
期刊：Gut
[BMJ]
日期：2022-04-01
卷期号：72 (1): 168-179
被引量：27
标识
DOI：10.1136/gutjnl-2021-326076
摘要
Alcoholic hepatitis (AH) reflects acute exacerbation of alcoholic liver disease (ALD) and is a growing healthcare burden worldwide. Interleukin-11 (IL-11) is a profibrotic, proinflammatory cytokine with increasingly recognised toxicities in parenchymal and epithelial cells. We explored IL-11 serum levels and their prognostic value in patients suffering from AH and cirrhosis of various aetiology and experimental ALD.
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