姜黄
微乳液
萃取(化学)
化学
响应面法
色谱法
薄荷醇
共晶体系
姜黄素
核化学
有机化学
传统医学
肺表面活性物质
医学
生物化学
合金
作者
Kantapich Kongpol,Namfa Sermkaew,Fonthip Makkliang,Sirinan Khongphan,Litavadee Chuaboon,Attapon Sakdamas,Seiichi Sakamoto,Waraporn Putalun,Gorawit Yusakul
出处
期刊:Food Chemistry
[Elsevier]
日期:2022-12-01
卷期号:396: 133728-133728
被引量:15
标识
DOI:10.1016/j.foodchem.2022.133728
摘要
The extraction of curcuminoids and aromatic (ar)-turmerone from Curcuma longa L. using organic solvents produces chemical waste, and is therefore incompatible with food applications. To address this issue, this study presents the design of hydrophobic deep eutectic solvents (HDESs) and HDES-based microemulsions. Using the response surface methodology (RSM), the optimal extraction conditions were identified as follows: HDES = OA:menthol (1:3.6 M ratio), solid-to-liquid ratio = 10:1 (mg/mL), and extraction duration = 90 min (prediction accuracy ≥ 85 %). Under these conditions, the HDES extraction yields of bisdemethoxycurcumin, demethoxycurcumin, curcumin, and ar-turmerone were 2.49 ± 0.25, 5.61 ± 0.45, 9.40 ± 0.86, and 3.83 ± 0.19 % (w/w, dry basis), respectively, while those obtained using the HDES-based microemulsion were 2.10 ± 0.18, 6.31 ± 0.48, 12.6 ± 1.20, and 2.58 ± 0.19 % (w/w, dry basis), respectively. The HDES and its microemulsions are more effective and environmentally friendly than conventional organic solvents for the extraction of curcuminoids and ar-turmerone, and these solvents are also compatible with food and pharmaceutical formulations.
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