Two-Dimensional TiVC Solid-Solution MXene as Surface-Enhanced Raman Scattering Substrate

and femtomolar-level detection limit were confirmed using rhodamine 6G as a model dye with 532 nm excitation. The fluorescent signal of the rhodamine 6G dye was effectively quenched, making the SERS spectrum clearly distinguishable. Furthermore, we demonstrate that the TiVC-analyte system with ultrahigh sensitivity is dominated by the chemical mechanism (CM) based on the experimental and simulation results. The abundant density of states near the Fermi level of the TiVC and the strong interaction between the TiVC and analyte promote the intermolecular charge transfer resonance in the TiVC-analyte complex, resulting in significant Raman enhancement. Additionally, several other probe molecules were used for SERS detection to further verify CM-based selectivity enhancement on the TiVC substrates. This work provides guidance for the facile synthesis of 2D MXene and its application in ultrasensitive SERS detection.