溶瘤病毒
癌症研究
病毒
病毒学
医学
胶质瘤
溶癌病毒
脑瘤
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2021-06-01
标识
DOI:10.1158/2159-8290.cd-nb2021-0332
摘要
In a small trial involving children with progressive high-grade gliomas, direct infusions of a genetically engineered strain of herpes simplex virus elicited responses in 11 of 12 recipients. The therapy also led to more than a doubling in average patient survival compared with historical expectations.
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