Computer-Based 3D MR Imaging Analysis in Amyotrophic Lateral Sclerosis: Common and Specific Factors Among Studies

Computerized MR imaging analysis including automatic measurements of whole-brain atrophy and the use of unbiased analysis techniques for regional atrophy without prior restriction of the search volume (such as voxel-based morphometry [VBM]) is a rapidly growing field in neuroimaging. Recently,