Integrated Characterization and Pharmacokinetics of Kanli Granule in Rats Based on UPLC‐Q‐TOF‐MS/MS: In Vitro and In Vivo Component Screening

< 1 h), with paeoniflorin and atractylenolide III showing significantly higher systemic exposure. Notably, the AUC of hypaconine and mangiferin was markedly greater in female rats, indicating a gender-related difference in metabolism. This work provides the first comprehensive chemical composition spectrum of KLG and clarifies its potential bioactive compounds, offering new insights for the material basis research and active component screening of Chinese herbal medicine compound preparations.