A berberine-loaded hydrogel for the treatment of atopic dermatitis through antibacterial activity, inhibition of inflammation and modulation of oxidative stress

The BHG exhibits favorable biocompatibility and potent antibacterial activity, and is capable of restoring the skin barrier and ameliorating dermatological symptoms in AD mice. Its anti-inflammatory and antioxidant effects may be mediated through modulation of the PI3K/AKT/NF-κB signaling pathway.